Proliferation and Carcinogenesis

This course will cover the basic tenets of cell biology as they apply to cancer. Topics to be covered will include the cell cycle, how cells normally grow and divide, how they stop growing and how that process is disrupted in cancer; the normal processes associated with cell death such as autophagy, apoptosis and necrosis; the concepts of “stemness” and immortalization in relation to cancer cells and the role of telomerase, mutagens, environmental toxins and DNA repair.